Scientific Papers

  • Klare K, Weir JR, Basilico F, Zimniak T, Massimiliano L, Ludwigs N, Herzog F, Musacchio A (2015) CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores. J Cell Biol 210: 11-22

  • Martinez-Rucobo FW, Kohler R, van de Waterbeemd M, Heck AJ, Hemann M, Herzog F, Stark H, Cramer P (2015) Molecular Basis of Transcription-Coupled Pre-mRNA Capping. Mol Cell 58: 1079-1089

  • Grimm M, Zimniak T, Kahraman A, Herzog F (2015) xVis: a web server for the schematic visualization and interpretation of crosslink-derived spatial restraints. Nucleic Acids Res 43: W362-369

  • Mulholland CB, Smets M, Schmidtmann E, Leidescher S, Markaki Y, Hofweber M, Qin W, Manzo M, Kremmer E, Thanisch K, Bauer C, Rombaut P, Herzog F, Leonhardt H, Bultmann S (2015) A modular open platform for systematic functional studies under physiological conditions. Nucleic Acids Res

  • Plaschka C, Lariviere L, Wenzeck L, Seizl M, Hemann M, Tegunov D, Petrotchenko EV, Borchers CH, Baumeister W, Herzog F, Villa E, Cramer P (2015) Architecture of the RNA polymerase II-Mediator core initiation complex. Nature 518: 376-380

  • Kock M, Nunes MM, Hemann M, Kube S, Jurgen Dohmen R, Herzog F, Ramos PC, Wendler P (2015) Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperone. Nat Commun 6: 6123

  • Huis in 't Veld PJ, Herzog F, Ladurner R, Davidson IF, Piric S, Kreidl E, Bhaskara V, Aebersold R, Peters JM (2014) Characterization of a DNA exit gate in the human cohesin ring. Science 346: 968-972


  • Kube S, Kapitein N, Zimniak T, Herzog F, Mogk A, Wendler P (2014) Structure of the VipA/B Type VI Secretion Complex Suggests a Contraction-State-Specific Recycling Mechanism. Cell Rep 8: 20-30

  • Hornung P, Troc P, Malvezzi F, Maier M, Demianova Z, Zimniak T, Litos G, Lampert F, Schleiffer A, Brunner M, Mechtler K, Herzog F, Marlovits TC, Westermann S (2014) A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A. J Cell Biol 206: 509-524

  • Basilico F, Maffini S, Weir JR, Prumbaum D, Rojas AM, Zimniak T, De Antoni A, Jeganathan S, Voss B, van Gerwen S, Krenn V, Massimiliano L, Valencia A, Vetter IR, Herzog F, Raunser S, Pasqualato S, Musacchio A (2014) The pseudo GTPase CENP-M drives human kinetochore assembly. Elife (Cambridge) 3: e02978


  • Muhlbacher W, Sainsbury S, Hemann M, Hantsche M, Neyer S, Herzog F$, Cramer P$ (2014) Conserved architecture of the core RNA polymerase II initiation complex. Nat Commun 5: 4310


  • Maiolica A, de Medina-Redondo M, Schoof EM, Chaikuad A, Villa F, Gatti M, Jeganathan S, Lou HJ, Novy K, Hauri S, Toprak UH, Herzog F, Meraldi P, Penengo L, Turk BE, Knapp S, Linding R, Aebersold R (2014) Modulation of the chromatin phosphoproteome by the haspin protein kinase. Mol Cell Proteomics : MCP 13: 1724-1740

  • Herzog F (2014) Measuring spatial restraints on native protein complexes using isotope-tagged chemical cross-linking and mass spectrometry. Method Mol Biol (Clifton, NJ) 1091: 259-273

  • Tosi A*, Haas C*, Herzog F*, Gilmozzi A, Berninghausen O, Ungewickell C, Gerhold CB, Lakomek K, Aebersold R, Beckmann R, Hopfner KP (2013) Structure and Subunit Topology of the INO80 Chromatin Remodeler and Its Nucleosome Complex. Cell 154: 1207-1219


  • Pfaff J, Hennig J, Herzog F, Aebersold R, Sattler M, Niessing D, Meister G (2013) Structural features of Argonaute-GW182 protein interactions. Proc Natl Acad Sci U S A 110: E3770-E3779

  • Kahraman A*, Herzog F*, Leitner A, Rosenberger G, Aebersold R, Malmstrom L (2013) Cross-Link Guided Molecular Modeling with ROSETTA. PloS one 8: e73411

  • Ciferri C, Lander GC, Maiolica A, Herzog F, Aebersold R, Nogales E (2012) Molecular architecture of human polycomb repressive complex 2. Elife 1: e00005

  • Herzog F*, Kahraman A*, Boehringer D*, Mak R, Bracher A, Walzthoeni T, Leitner A, Beck M, Hartl FU, Ban N, Malmstrom L, Aebersold R (2012) Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry. Science 337: 1348-1352


  • Wu CC, Herzog F, Jennebach S, Lin YC, Pai CY, Aebersold R, Cramer P, Chen HT (2012) RNA polymerase III subunit architecture and implications for open promoter complex formation. Proc Natl Acad Sci U S A 109: 19232-19237

  • Walzthoeni T, Claassen M, Leitner A, Herzog F, Bohn S, Forster F, Beck M, Aebersold R (2012) False discovery rate estimation for cross-linked peptides identified by mass spectrometry. Nat Methods 9: 901-903

  • Escher C, Reiter L, MacLean B, Ossola R, Herzog F, Chilton J, MacCoss MJ, Rinner O (2012) Using iRT, a normalized retention time for more targeted measurement of peptides. Proteomics 12: 1111-1121

  • Jennebach S*, Herzog F*, Aebersold R, Cramer P (2012) Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage. Nucleic Acids Res 40: 5591-5601

  • Leitner A, Reischl R, Walzthoeni T, Herzog F, Bohn S, Foerster F, Aebersold R (2012) Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatography. Mol Cell Proteomics

  • Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R (2011) The quantitative proteome of a human cell line. Mol Syst Biol 7: 549

  • Blattner C, Jennebach S, Herzog F, Mayer A, Cheung AC, Witte G, Lorenzen K, Hopfner KP, Heck AJ, Aebersold R, Cramer P (2011) Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes Dev 25: 2093-2105

  • Buschhorn BA, Petzold G, Galova M, Dube P, Kraft C, Herzog F, Stark H, Peters JM (2011) Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1. Nat Struct Mol Biol 18: 6-13

  • Leitner A, Walzthoeni T, Kahraman A, Herzog F, Rinner O, Beck M, Aebersold R (2010) Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics. Mol Cell Proteomics 9: 1634-1649


  • Herzog F, Primorac I, Dube P, Lenart P, Sander B, Mechtler K, Stark H, Peters JM (2009) Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science 323: 1477-1481


  • Kastner B, Fischer N, Golas MM, Sander B, Dube P, Boehringer D, Hartmuth K, Deckert J, Hauer F, Wolf E, Uchtenhagen H, Urlaub H, Herzog F, Peters JM, Poerschke D, Luhrmann R, Stark H (2008) GraFix: sample preparation for single-particle electron cryomicroscopy. Nat Methods 5: 53-55

  • Mazanek M, Mituloviae G, Herzog F, Stingl C, Hutchins JR, Peters JM, Mechtler K (2007) Titanium dioxide as a chemo-affinity solid phase in offline phosphopeptide chromatography prior to HPLC-MS/MS analysis. Nat Protoc 2: 1059-1069

  • Dube P, Herzog F, Gieffers C, Sander B, Riedel D, Muller SA, Engel A, Peters JM, Stark H (2005) Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Mol Cell 20: 867-879

  • Herzog F, Mechtler K, Peters JM (2005) Identification of cell cycle-dependent phosphorylation sites on the anaphase-promoting complex/cyclosome by mass spectrometry. Method Enzymol 398: 231-245

  • Herzog F, Peters JM (2005) Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome. Method Enzymol 398: 175-195

  • Acquaviva C, Herzog F, Kraft C, Pines J (2004) The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint. Nat Cell Biol 6: 892-898

  • Kraft C, Herzog F, Gieffers C, Mechtler K, Hagting A, Pines J, Peters JM (2003) Mitotic regulation of the human anaphase-promoting complex by phosphorylation. EMBO J 22: 6598-6609

↑ to the top